The Frat Boys were a group of sociopathic individuals who attended college in Champion City and lived in the same frat house. They loved the party lifestyle of their fraternity so much that, some time before 1979, they formed a gang called the Frat Boys. They made a name for themselves commiting various crimes. Their group was recruited, along with many other gangs, by the criminal mastermind Casanova Frankenstein in his attempts to conquer Champion city. At some point, during the course of harassing one or more people, they caused at least one fatality. They were all arrested for manslaughter. They were all eventually released on parole for good behavior, despite their lack of remorse. When Casanova Frankenstein was apprehended by Captain Amazing in 1979, the Frat Boys disbanded. In 1999, the Frat Boys are reunited by a recently released Casanova Frankenstein, who called for a meeting between all of his former gangs, including the Disco Boys, the Furriers, the Suits (including their leader, Big Tobacco), the Susies and the Not-So-Goodie Mob. They are told of Casanova's new weapon, the Psycho-frakulator and his plans for world domination. The Frat Boys witness the end results of the machine's power after they are shown Captain Amazing's dead body. When the Mystery Men attack Casanova's mansion, the Frat Boys fight, but are ultimately overpowered. They attempt to flee with Casanova Frankenstein, but he activates his mansion's defenses before they are clear, causing them to be elcetrocuted and killed.
- Metal Pole: Wielded by at least one member of the Frat Boys before their they're kiilled.